Released on = April 23, 2007, 8:53 pm

Press Release Author = Synamatix

Industry = Biotech

Press Release Summary = Synamatix announced today the release of two new software
applications designed to process and analyse data from large-scale re-sequencing
projects conducted with second generation DNA sequencing platforms.

Press Release Body = Kuala Lumpur, 24 April, 2007 - Synamatix announced today the
release of two new software applications designed to process and analyse data from
large-scale re-sequencing projects conducted with second generation DNA sequencing
platforms.

Robert Hercus, Synamatix Managing Director, commented, "SXOligosearchT and a
modified version of SynaSearchT have been released to address the growing explosion
of data from the increasing use of the 454-Roche and Solexa-Illumina DNA sequencing
platforms.
These applications were developed as part of an ongoing strategy to complete a suite
of
high-throughput applications to process, analyse and integrate data from every type of
second generation DNA sequencer."

The first application, SXOligosearch, is designed to map short sequences such as
reads from the Solexa-Illumina genome sequencer or oligonucleotide microarray
probes. It offers a very high degree of flexibility in terms of handling a wide
variety of read errors or mutations. In addition, more than a 100-fold improvement
in performance compared to conventional tools is observed. Unlike other industry
standard alignment tools, SXOligosearch aligns complete reads rather than HSPs
resulting in higher specificity and sensitivity. It is also able to handle
low-quality reads containing any number of mismatches, insertions or deletions with
high accuracy and superior performance.

A new version of SynaSearch, modified to process and map reads from the GS20 and FLX
platforms from 454, has also been released. Careful optimisation has resulted in
increased accuracy, specificity and a 200-fold improvement in performance compared
to standard approaches.

By using SynaBASET as a common platform, various types of reads can be mixed to
increase coverage and deepen support for differences that are identified between
data sets.

Synamatix's other high-performance applications based upon SynaBASE, its unique
structured network database platform, include SynaTreeT, SXPRESearchT and
SXProbeDBT.

About Synamatix
The fundamental technology underlying Synamatix software applications is the
proprietary "SynaBASE" platform. Applications built upon this database platform
exhibit very significant improvement in scalability, sensitivity and performance.
Synamatix is a privately held next-generation bioinformatics company whose primary
activities are based upon ongoing R&D related to its core technology, development of
new software applications, and the support of its user base in the USA, Europe, Asia
and Australia.



Web Site = http://www.synamatix.com

Contact Details = Patricia Chan
Marketing and Communications
Synamatix
27-9, Level 9, Signature Office,
Bandar Mid-Valley,
59200 Kuala Lumpur, Malaysia
enquiries@synamatix.com